ESPE Yearbook of Paediatric Endocrinology

ESPE Yearbook of Paediatric Endocrinology

ISSN 1662-4009 (online)

Published by BioScientifica

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ey0018.10-9 | (1) | ESPEYB18

10.9. Serum 25-hydroxyvitamin D concentration in childhood and risk of islet autoimmunity and type 1 diabetes: the TRIGR nested case-control ancillary study

ME Miettinen , S Niinisto , I Erlund , D Cuthbertson , AM Nucci , J Honkanen , O Vaarala , H Hyoty , JP Krischer , M Knip

Diabetologia. 2020;63(4):780–787. doi: 10.1007/s00125-019-05077-4.This multicenter multinational study, in children with high genetic risk of T1D, identified an association between lower serum 25-hydroxyvitamin D (25OHD) concentrations and subsequent appearance of islet autoimmunity or T1D.The Trial to Reduce IDDM in the Genetically at Risk (TRIGR) ancillary ...
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ey0017.10-5 | (1) | ESPEYB17

10.5. Association of cereal, gluten, and dietary fiber intake with islet autoimmunity and type 1 diabetes

L Hakola , ME Miettinen , E Syrjala , M Akerlund , M-H Takkinen , TE Korhonen , S Ahonen , J Ilonen , J Toppari , R Veijola , J Nevelainen , M Knip , SM Virtanen

To read the full abstract: JAMA Pediatr 2019; 173:953–960.Dietary proteins, such as gluten, have been suggested to serve as triggers of the autoimmune process that leads to type 1 diabetes (T1DM). These authors studied the potential associations of cereal, gluten, and dietary fiber intake with the development of islet autoimmunity (IA) and T1DM.The prospective birth cohort Finnish Type 1 Diabetes Prediction and Preven...
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ESPE Yearbook of Paediatric Endocrinology
ISSN 1662-4009 (Online)
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